MOTS-c: Half-Life, Tracking & Reference
Commonly tracked in metabolic or performance-focused cycles.
| Category | Metabolic Support |
|---|---|
| Typical half-life | about 3 hours |
| Essentially cleared in | roughly 15 hours (~5 half-lives) |
| Common routes | Injection |
Half-life, explained with MOTS-c's numbers
A half-life of about 3 hours means that after that much time, about half of an absorbed amount remains. Each additional half-life halves it again:
| Elapsed time | Estimated amount remaining |
|---|---|
| 1 half-life (3 hours) | 50% remaining |
| 2 half-lives (6 hours) | 25% remaining |
| 3 half-lives (9 hours) | 12.5% remaining |
| 4 half-lives (12 hours) | 6.25% remaining |
| 5 half-lives (15 hours) | 3.125% remaining |
This is why spacing and consistency matter more than any single dose time, and why short-half-life compounds are often scheduled more frequently than long ones. You can see this curve for your own logged schedule in the levels visualizer or automatically in the app.
What it’s tracked for
- Cycle tracking
- Energy log pairing
Reported side effects
- Fatigue
- Injection discomfort
Safety notes
Cycle and dosing details should remain provider-directed.
- Review metabolic history with a provider
Often tracked alongside
- Often logged with exercise or nutrition notes
Research context
- Mitochondrial peptide studies
Frequently asked questions
- What is the half-life of MOTS-c?
- The commonly referenced elimination half-life of MOTS-c is about 3 hours. Half-life is the time it takes for the amount of a compound in the body to fall by half; it is the basis for estimating how levels rise and fall between doses.
- How long does MOTS-c stay in your system?
- As a rule of thumb, a compound is considered essentially cleared after about five half-lives. For MOTS-c, with a half-life of about 3 hours, that works out to roughly 15 hours. Individual factors like metabolism, dose, and route of administration all shift this, so treat it as an estimate, not a measurement.
- How is MOTS-c administered?
- MOTS-c is most commonly tracked with these routes: Injection. Route affects how quickly a compound is absorbed and how long it acts; your provider determines what is appropriate for you.
- What do people track MOTS-c for?
- Commonly tracked in metabolic or performance-focused cycles. PeptideWiz is a tracking tool: it records what you and your provider have decided, and does not recommend any compound or dose.
Not medical advice. This page is an educational reference
for people who track provider-directed protocols. It does not recommend MOTS-c or any
dose, and half-life figures are commonly cited estimates that vary between individuals and
formulations. Always work with a licensed medical provider.